{"id":872,"date":"2026-04-23T23:49:24","date_gmt":"2026-04-23T23:49:24","guid":{"rendered":"https:\/\/decodepeptides.com\/?product=epithalon-10mg"},"modified":"2026-05-29T01:10:58","modified_gmt":"2026-05-29T01:10:58","slug":"epithalon-10mg","status":"publish","type":"product","link":"https:\/\/decodepeptides.com\/de\/product\/epithalon-10mg\/","title":{"rendered":"Epithalon 10 mg"},"content":{"rendered":"

Epithalon<\/strong> (tetrapeptide Ala-Glu-Asp-Gly) was developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology from pineal gland extract. It is one of the best-documented anti-aging peptides in the world, with over 30 years of peer-reviewed research demonstrating direct telomerase activation, epigenetic reprogramming of senescent cells, melatonin restoration, and significant lifespan extension in multiple model organisms. Its ability to increase telomere length in human somatic cells makes it the leading research tool for telomere biology and biological age reversal studies.<\/p>\n

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\u226599%<\/span>HPLC-Reinheit<\/span><\/div>\n
10 mg<\/span>Von Vial<\/span><\/div>\n
30+<\/span>Jahre der Recherche<\/span><\/div>\n
4 aa<\/span>Struktur<\/span><\/div>\n<\/div>\n
\"Epithalon\"Epithalon<\/div>\n

Forschungsdaten<\/span><\/p>\n

Research Snapshot \u2014 Epithalon<\/h2>\n

Schl\u00fcsselmechanismen und Signalwege<\/h3>\n
    \n
  • Telomerase (hTERT) Activation<\/strong>Directly upregulates telomerase, extending telomeric DNA repeats and reversing cellular senescence.<\/li>\n
  • Pineal Gland Normalisation<\/strong>Restores melatonin synthesis in aged pinealocytes, resetting circadian and immune regulation.<\/li>\n
  • Antioxidant Gene Upregulation<\/strong>Increases SOD, catalase and glutathione peroxidase \u2014 the primary enzymatic antioxidant defence system.<\/li>\n
  • Epigenetic Reprogramming<\/strong>Reactivates methylation-silenced tumour suppressor genes p16 and p21.<\/li>\n
  • Neuroendocrine Axis Reset<\/strong>Restores hypothalamic receptor sensitivity to sex steroid feedback, normalising age-related hormonal decline.<\/li>\n
  • NK Cell Activation<\/strong>Enhanced natural killer cell cytotoxicity and restored thymic activity in aged rodent models.<\/li>\n<\/ul>\n

    Zusammenfassung der pr\u00e4klinischen und klinischen Forschung<\/h3>\n\n\n\n\n\n\n\n\n
    Forschungsgebiet<\/th>\nWichtigste Erkenntnis<\/th>\nQuelle<\/th>\n<\/tr>\n<\/thead>\n
    Telomere Elongation<\/td>\n+42% replicative lifespan of human fetal fibroblasts vs. controls via hTERT activation.<\/td>\nKhavinson et al., 2003 \u2014 Bull Exp Biol Med<\/td>\n<\/tr>\n
    Lifespan Extension<\/td>\nExtended Drosophila mean lifespan by 11\u201316%; maximum lifespan by 13%.<\/td>\nKhavinson et al., 2000 \u2014 Bull Exp Biol Med<\/td>\n<\/tr>\n
    Cancer Prevention<\/td>\nReduced spontaneous mammary tumour incidence by 2.4\u00d7 in HER2-transgenic mice.<\/td>\nAnisimov VN et al., 2003 \u2014 Biogerontology<\/td>\n<\/tr>\n
    Cardiovascular<\/td>\nReduced cardiovascular mortality in 12-year longitudinal study of elderly patients.<\/td>\nKhavinson et al., 2012 \u2014 Gerontology<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n

    Referenzen<\/h3>\n
      \n
    1. Khavinson VKh et al. “Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.” Bull Exp Biol Med<\/em>, 2003;135(6):590\u2013592.<\/li>\n
    2. Anisimov VN et al. “Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence.” Biogerontology<\/em>, 2003;4(4):193\u2013202.<\/li>\n
    3. Kossoy G et al. “Effect of epithalon on the lifespan and frequency of spontaneous mammary gland tumors in transgenic HER2 mice.” Neoplasma<\/em>, 2006;53(3):187\u2013192.<\/li>\n
    4. Khavinson V et al. “Tetrapeptide AEDG (Epitalon) inhibits oxidative stress.” Regul Toxicol Pharmacol<\/em>, 2014;70(1):289\u2013294.<\/li>\n<\/ol>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

      Epithalon (Epitalon) ist ein synthetisches Tetrapeptid (Ala-Glu-Asp-Gly), das aus dem nat\u00fcrlichen Zirbeldr\u00fcsenpeptid Epithalamin entwickelt wurde. Es z\u00e4hlt zu den am besten erforschten Anti-Aging-Peptiden und wurde vor allem aufgrund seiner F\u00e4higkeit untersucht, die Telomeraseaktivit\u00e4t zu stimulieren, Telomere zu verl\u00e4ngern und den zirkadianen Rhythmus zu regulieren. Jede Durchstechflasche enth\u00e4lt 10 mg Epithalon in Forschungsqualit\u00e4t.<\/p>","protected":false},"featured_media":2115,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"product_brand":[],"product_cat":[56],"product_tag":[213,218,216,217,256,214,254,211,255,215],"class_list":["post-872","product","type-product","status-publish","has-post-thumbnail","product_cat-anti-aging-longevity","product_tag-anti-aging","product_tag-cellular-senescence","product_tag-dna-repair","product_tag-epigenetic-reset","product_tag-hplc-verified","product_tag-longevity","product_tag-lyophilized-powder","product_tag-neuroprotection","product_tag-research-grade","product_tag-telomere-support","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product\/872","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/comments?post=872"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/media\/2115"}],"wp:attachment":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/media?parent=872"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product_brand?post=872"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product_cat?post=872"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product_tag?post=872"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}