{"id":873,"date":"2026-04-23T23:49:25","date_gmt":"2026-04-23T23:49:25","guid":{"rendered":"https:\/\/decodepeptides.com\/?product=ghk-cu"},"modified":"2026-05-29T01:10:58","modified_gmt":"2026-05-29T01:10:58","slug":"ghk-cu","status":"publish","type":"product","link":"https:\/\/decodepeptides.com\/de\/product\/ghk-cu\/","title":{"rendered":"GHK-Cu (Kupferpeptid) 100 mg"},"content":{"rendered":"

GHK-Cu<\/strong> (Glycine-Histidine-Lysine copper complex) was first isolated from human plasma albumin in 1973 by Pickart and Thaler. Its plasma concentration declines from ~200 ng\/mL at age 20 to under 80 ng\/mL by age 60 \u2014 a decline directly correlated with reduced tissue repair capacity. A landmark 2012 study demonstrated that GHK-Cu modulates the expression of 32% of the human genome<\/strong>, making it one of the most wide-ranging regulatory peptides ever characterised. Research applications span wound healing, skin regeneration, hair growth, pulmonary fibrosis, neural repair, and anti-cancer gene expression.<\/p>\n

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\u226599%<\/span>HPLC-Reinheit<\/span><\/div>\n
100mg<\/span>Von Vial<\/span><\/div>\n
50+<\/span>Jahre der Recherche<\/span><\/div>\n
3 aa<\/span>Struktur<\/span><\/div>\n<\/div>\n
\"GHK-Cu\"GHK-Cu<\/div>\n

Forschungsdaten<\/span><\/p>\n

Research Snapshot \u2014 GHK-Cu (Copper Peptide)<\/h2>\n

Schl\u00fcsselmechanismen und Signalwege<\/h3>\n
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  • Collagen I, III & VI Synthesis<\/strong>Upregulates COL1A1, COL3A1 and decorin \u2014 structural collagen genes critical for skin, tendon and wound repair.<\/li>\n
  • Genomic Reprogramming<\/strong>Modulates expression of 32% of the human genome via VEGF, HGF and anti-inflammatory cytokine gene activation.<\/li>\n
  • MMP \/ TIMP Balance<\/strong>Simultaneously activates MMPs for remodelling and TIMPs for protection \u2014 balanced ECM turnover, not degradation.<\/li>\n
  • Copper-SOD Activation<\/strong>Delivers Cu\u00b2\u207a to superoxide dismutase and lysyl oxidase, driving antioxidant defence and collagen crosslinking.<\/li>\n
  • VEGF & FGF-2 Induction<\/strong>Stimulates angiogenic and fibroblast growth factors, accelerating wound vascularisation and closure.<\/li>\n
  • Neural Regeneration<\/strong>Promotes axonal outgrowth and BDNF expression; used in CNS injury and neuropathy research models.<\/li>\n<\/ul>\n

    Zusammenfassung der pr\u00e4klinischen und klinischen Forschung<\/h3>\n\n\n\n\n\n\n\n\n
    Forschungsgebiet<\/th>\nWichtigste Erkenntnis<\/th>\nQuelle<\/th>\n<\/tr>\n<\/thead>\n
    Skin Regeneration<\/td>\nIncreased skin thickness by 120% and collagen density by 70% in aged skin models.<\/td>\nAbdulghani AA et al., 1998 \u2014 J Dermatol Surg<\/td>\n<\/tr>\n
    Wundheilung<\/td>\nAccelerated healing of chronic leg ulcers; improved wound contraction rates clinically.<\/td>\nLeyden JJ et al., 1990<\/td>\n<\/tr>\n
    Hair Growth<\/td>\nEnlarged follicle size; increased KGF (keratinocyte growth factor) expression in vivo.<\/td>\nUno H et al., 1996<\/td>\n<\/tr>\n
    Lung Protection<\/td>\nAttenuated bleomycin-induced pulmonary fibrosis by reducing TGF-\u03b21 and collagen deposition.<\/td>\nCampbell JD et al., 2019<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n

    Referenzen<\/h3>\n
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    1. Pickart L et al. “The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging.” Oxid Med Cell Longev<\/em>, 2012;2012:324832.<\/li>\n
    2. Pickart L, Margolina A. “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” Int J Mol Sci<\/em>, 2018;19(7):1987.<\/li>\n
    3. Gorouhi F, Maibach HI. “Role of topical peptides in preventing or treating aged skin.” Int J Cosmet Sci<\/em>, 2009;31(5):327\u2013345.<\/li>\n
    4. Canapp SO et al. “The effect of topical tripeptide-copper complex on healing of ischemic open wounds.” Vet Surg<\/em>, 2003;32(6):515\u2013523.<\/li>\n<\/ol>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

      GHK-Cu (Glycyl-L-histidyl-L-lysin-Kupfer-Komplex) ist ein nat\u00fcrlich vorkommendes, kupferbindendes Tripeptid im menschlichen Plasma. Es z\u00e4hlt zu den am besten untersuchten Peptiden in der regenerativen Biologie, der kosmetischen Dermatologie und der Wundheilungsforschung. Jede Durchstechflasche enth\u00e4lt 100 mg GHK-Cu in Forschungsqualit\u00e4t als lyophilisiertes Pulver.<\/p>","protected":false},"featured_media":2116,"comment_status":"open","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"product_brand":[],"product_cat":[56,55],"product_tag":[212,209,235,239,237,256,254,255,236,238],"class_list":["post-873","product","type-product","status-publish","has-post-thumbnail","product_cat-anti-aging-longevity","product_cat-recovery-healing","product_tag-angiogenesis","product_tag-anti-inflammatory","product_tag-collagen-synthesis","product_tag-copper-peptide","product_tag-hair-growth","product_tag-hplc-verified","product_tag-lyophilized-powder","product_tag-research-grade","product_tag-skin-health","product_tag-wound-repair","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product\/873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/comments?post=873"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/media\/2116"}],"wp:attachment":[{"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/media?parent=873"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product_brand?post=873"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product_cat?post=873"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/decodepeptides.com\/de\/wp-json\/wp\/v2\/product_tag?post=873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}