
Thymosin Alpha-1 10mg
Thymosin Alpha-1 is a 28-amino-acid thymic peptide studied as an immune modulator acting through Toll-like receptors and T-cell maturation. This research vial contains 10mg, ≥99% HPLC purity.
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Independent EU lab, ≥99% HPLC
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Plain outer box, no branding
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About this compound
What Is Thymosin Alpha-1?
Thymosin Alpha-1 (Tα1) is a 28-amino-acid N-terminally acetylated peptide originally isolated from thymosin fraction 5 of bovine thymus. It is one of the most extensively studied immunomodulatory peptides in the world and is approved in more than thirty countries under the name Zadaxin for hepatitis B and C and as a vaccine adjuvant.
Key Mechanisms
- TLR2 and TLR9 signalling — activates dendritic cells and shapes the innate-to-adaptive immune handoff
- T-cell maturation — promotes differentiation of thymocytes into functional CD4+ and CD8+ T cells
- Th1 polarisation — raises IL-2 and interferon-γ, strengthening cell-mediated immunity
- NK-cell and dendritic-cell activation — enhances antigen presentation and cytotoxic surveillance
- Immune restraint — also studied for damping excessive inflammatory responses, giving it a bidirectional regulatory profile
Research Applications
- Chronic viral infection models (hepatitis B and C)
- Vaccine adjuvant and immune-response research
- Immunosenescence and age-related immune decline
- Sepsis and dysregulated inflammatory-response studies
Handling
Supplied lyophilized. Reconstitute with bacteriostatic water. Store the sealed vial at 2–8 °C; refrigerate after reconstitution and use within 28 days.
Supplied strictly for laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption.
Specifications
- Sequence
- Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
- Molecular Weight
- 3108.5 Da
- Amino Acids
- 28
- Half-Life
- ~2 hours
- CAS Number
- 62304-98-7
- Vial Size
- 10mg
- Purity
- ≥99% (HPLC)
- Form
- Lyophilized powder
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol)
- Storage
- Sealed: 2–8 °C · Reconstituted: 2–8 °C, use within 28 days
Research library
Full mechanism breakdowns and peer-reviewed references for this compound.
Frequently asked questions
Related research compounds
For laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption. By purchasing, you confirm you are a qualified researcher and accept full responsibility for compliant handling and disposal. Read the full disclaimers.

