5-Amino-1MQ 10mg
5-Amino-1MQ is a small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor studied for its effects on cellular NAD+ pools and adipocyte metabolism. This research vial contains 10mg, ≥99% HPLC purity.
Volume pricing — buy more, pay less per vial
Select a tier to set the quantity. Discount is applied automatically at checkout.
COA with every batch
Independent EU lab, ≥99% HPLC
Secure encrypted checkout
Card payments over TLS
Discreet packaging
Plain outer box, no branding
EU dispatch in 24–48h
Tracked delivery
Cold-chain handling
Temperature-controlled transit
About this compound
What Is 5-Amino-1MQ?
5-Amino-1MQ (5-amino-1-methylquinolinium) is a cell-permeable small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT consumes nicotinamide — an NAD+ precursor — and is markedly overexpressed in the adipose tissue of obese metabolic models. Inhibiting it is studied as a route to preserving intracellular NAD+ without exogenous NAD+ administration.
Key Mechanisms
- NNMT inhibition — blocks methylation of nicotinamide, sparing it for NAD+ salvage
- NAD+ pool preservation — raises intracellular NAD+ and, downstream, sirtuin activity
- Adipocyte metabolism — research reports reduced adipocyte size and increased lipolysis in diet-induced obesity models
- Selective tissue action — NNMT expression is concentrated in adipose and liver tissue
Research Applications
- NAD+ biology and sirtuin-pathway research
- Diet-induced obesity and adipocyte studies
- Metabolic-syndrome and insulin-resistance models
- Comparative work alongside direct NAD+ precursors
Handling
Supplied as lyophilized powder. Store the sealed vial at 2–8 °C protected from light and moisture.
Supplied strictly for laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption.
Specifications
- Compound Class
- Small molecule — NNMT inhibitor
- Full Name
- 5-amino-1-methylquinolinium
- Vial Size
- 10mg
- Purity
- ≥99% (HPLC)
- Form
- Lyophilized powder
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol)
- Storage
- Sealed: 2–8 °C · Reconstituted: 2–8 °C, use within 28 days
Frequently asked questions
Related research compounds
For laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption. By purchasing, you confirm you are a qualified researcher and accept full responsibility for compliant handling and disposal. Read the full disclaimers.