DSIP 2mg
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide studied for its role in slow-wave sleep architecture and stress-axis regulation. This research vial contains 2mg, ≥99% HPLC purity.
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COA with every batch
Independent EU lab, ≥99% HPLC
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About this compound
What Is DSIP?
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first isolated in 1977 from the cerebral venous blood of rabbits during electrically induced slow-wave sleep. Despite decades of study its receptor has never been definitively identified, yet it produces reproducible effects on sleep architecture and neuroendocrine output across species.
Key Mechanisms
- Delta-wave promotion — increases slow-wave (stage 3–4) sleep proportion in EEG studies
- HPA-axis modulation — attenuates stress-induced corticotropin and cortisol release
- Circadian influence — interacts with the pineal–hypothalamic axis and melatonin rhythm
- Antinociception — opioid-independent analgesic effects reported in animal models
Research Applications
- Sleep architecture and EEG studies
- Stress-response and cortisol regulation
- Circadian-rhythm research
- Chronic pain and withdrawal models
Handling
Supplied lyophilized. Reconstitute with bacteriostatic water. Store the sealed vial at 2–8 °C; refrigerate after reconstitution and use within 28 days.
Supplied strictly for laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption.
Specifications
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Molecular Weight
- 848.9 Da
- Amino Acids
- 9
- Half-Life
- ~30 minutes
- CAS Number
- 62568-57-4
- Vial Size
- 2mg
- Purity
- ≥99% (HPLC)
- Form
- Lyophilized powder
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol)
- Storage
- Sealed: 2–8 °C · Reconstituted: 2–8 °C, use within 28 days
Research library
Full mechanism breakdowns and peer-reviewed references for this compound.
Frequently asked questions
Related research compounds
For laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption. By purchasing, you confirm you are a qualified researcher and accept full responsibility for compliant handling and disposal. Read the full disclaimers.