Snap-8 10mg
SNAP-8 is an elongated acetyl octapeptide studied as a topical alternative to neurotoxin-mediated inhibition of SNARE complex assembly. This research vial contains 10mg, ≥99% HPLC purity.
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COA with every batch
Independent EU lab, ≥99% HPLC
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Plain outer box, no branding
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Cold-chain handling
Temperature-controlled transit
About this compound
What Is SNAP-8?
SNAP-8 (acetyl octapeptide-3) is an elongated derivative of Argireline (acetyl hexapeptide-8), extended from six to eight amino acids. It is modelled on the N-terminal end of the SNAP-25 protein and is studied in cosmetic science as a topical route to modulating the same vesicle-docking machinery that botulinum toxin cleaves — but through competitive interference rather than enzymatic destruction.
Key Mechanisms
- SNARE complex competition — mimics the N-terminal of SNAP-25 and competes for its position in the ternary SNARE assembly
- Reduced vesicle docking — a destabilised complex releases neurotransmitter less efficiently
- Catecholamine attenuation — studied for reduced catecholamine release at the neuromuscular junction
- Topical, non-enzymatic — unlike neurotoxins it does not proteolytically cleave the target protein
Research Applications
- Cosmetic-science and expression-line research
- SNARE-complex and exocytosis studies
- Topical peptide-delivery formulation work
- Comparative studies with acetyl hexapeptide-8
Handling
Supplied lyophilized. Store the sealed vial at 2–8 °C protected from light and moisture; refrigerate after reconstitution.
Supplied strictly for laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption.
Specifications
- Sequence
- Acetyl octapeptide-3 (SNAP-25 N-terminal mimetic)
- Amino Acids
- 8
- Vial Size
- 10mg
- Purity
- ≥99% (HPLC)
- Form
- Lyophilized powder
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol)
- Storage
- Sealed: 2–8 °C · Reconstituted: 2–8 °C, use within 28 days
Frequently asked questions
Related research compounds
For laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption. By purchasing, you confirm you are a qualified researcher and accept full responsibility for compliant handling and disposal. Read the full disclaimers.