WOLVERINE is a co-lyophilized blend of BPC-157 and TB-500, the two most-cited regenerative peptides in soft-tissue repair research, in a single vial. ≥99% HPLC purity.
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COA with every batch
Independent EU lab, ≥99% HPLC
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About this compound
What Is WOLVERINE?
WOLVERINE pairs BPC-157 and TB-500 — co-lyophilized in a single vial. This is the most frequently studied combination in soft-tissue repair research, because the two peptides act on genuinely different arms of the healing cascade rather than duplicating each other.
The Two Components
- BPC-157 — a 15-amino-acid pentadecapeptide derived from human gastric juice, with over 200 preclinical publications spanning tendon, muscle, gut, bone, CNS and vascular biology. Works through FAK-paxillin activation, VEGF upregulation, EGR-1-driven collagen expression and NF-κB inhibition.
- TB-500 — the synthetic active fragment of thymosin β4, a 43-amino-acid protein present in nearly all human cells. Its primary mechanism is G-actin sequestration, which mobilises cell migration, endothelial differentiation and new blood-vessel formation.
Why the Combination
BPC-157 handles local cellular signalling and angiogenic drive at the injury site; TB-500 governs the cytoskeletal machinery that lets progenitor cells actually migrate there. Researchers pair them because tissue repair requires both the instruction and the means to carry it out — a distinction visible in comparative single-agent versus combined studies.
Research Applications
- Tendon and ligament healing models (Achilles, rotator cuff)
- Muscle crush-injury and strain recovery
- Gastrointestinal ulcer and mucosal repair
- Post-surgical and post-injury recovery protocols
Handling
Supplied co-lyophilized in a single vial. Reconstitute with bacteriostatic water. Store the sealed vial at 2–8 °C; refrigerate after reconstitution and use within 28 days.
Supplied strictly for laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption.
Specifications
- Composition
- BPC-157 + TB-500 (co-lyophilized)
- Sequence
- BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- Molecular Weight
- BPC-157: 1419.5 Da · TB-500: 4963.5 Da
- Half-Life
- BPC-157: 4–6 h · TB-500: 5–7 days
- Vial Size
- Single blended vial
- Purity
- ≥99% (HPLC)
- Form
- Lyophilized powder
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol)
- Storage
- Sealed: 2–8 °C · Reconstituted: 2–8 °C, use within 28 days
Research library
Full mechanism breakdowns and peer-reviewed references for each compound in this blend.
🩹 BPC-157
Most Researched
A 15-amino-acid peptide derived from human gastric juice with extraordinary multi-tissue healing properties. One of the most cited research peptides, with 200+ preclinical studies.
🩹 TB500 (Thymosin Beta-4)
Popular Stack
Synthetic Thymosin Beta-4 analogue. Drives angiogenesis, G-actin sequestration and cell migration — the cornerstone of systemic tissue repair research.
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For laboratory and in-vitro research use only. Not for human or veterinary use, not for consumption. By purchasing, you confirm you are a qualified researcher and accept full responsibility for compliant handling and disposal. Read the full disclaimers.